Remember when your teachers told you never to use an ampersand (that’s the “and sign”) in place of the word and? Well, sometimes you should use an ampersand; when it appears in a title is one of those times.
Also, note the period replacing the comma after Dragons.
You and your friends are playing a game of Dungeons & Dragons. Your character goes through a portal in-game and appears right behind you in real life.
(CMS-16 says names of games such as computer games or those that are also written works — y’know, RPG books — should be italicized.)